Symbol
Name
ID

Il7r
interleukin 7 receptor
MGI:96562

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

increased thymocyte apoptosis

abnormal T cell proliferation

decreased T cell proliferation

small thymus

thymus hypoplasia

decreased thymocyte number

increased thymocyte number

abnormal B cell differentiation

decreased immature B cell number

arrested B cell differentiation

abnormal T cell differentiation

abnormal CD4-positive T cell differentiation

abnormal CD8-positive, alpha-beta T cell differentiation

increased double-negative T cell number

decreased double-positive T cell number

increased double-positive T cell number

abnormal gamma-delta T cell differentiation

arrested T cell differentiation

decreased bone marrow cell number

decreased mature B cell number

decreased B-1 B cell number

decreased B cell number

increased B cell number

abnormal T cell subpopulation ratio

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased NK T cell number

absent mature gamma-delta T cells

increased gamma-delta T cell number

decreased memory T cell number

decreased T cell number

decreased lymphocyte cell number

decreased leukocyte cell number

abnormal T cell morphology

spleen hypoplasia

abnormal CD4-positive, alpha-beta T cell physiology

Availability

Mouse Genotype

Il7r^tm1Abra/Il7r^tm1Abra

Il7r^tm1Iku/Il7r^tm1Iku

Il7r^tm1Imx/Il7r^tm1Imx

Il7r^tm1Imx/Il7r^tm1Imx
Tg(Lck-Il7r)1676Trma/?

Il7r^tm2Iku/Il7r^tm2Iku
Tg(Cd4-cre)1Cwi/? (conditional)

Il7r^tm1.1Asin/Il7r^tm1Imx
Tg(Cd4-cre)1Cwi/0 (conditional)

Il7r^tm1.1Asin/Il7r^tm1Imx
Tg(Cd8a*-cre)B8Asin/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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